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This is why our protocols at Perfect B are not single-compound prescriptions but layered combinations chosen for each patient
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doi: 10.1007/s13277-015-4004-z 176 NovysedlakRGuneyMAl KhouriMBartoliniRKoumbas FoleyLBenesovaIet al
Given that isotope tracer studies show BB is clearly formed following oral l-carnitine ingestion, and similarly, isotope-labeled BB was readily converted into isotope-labeled TMA/TMAO following oral ingestion, we hypothesized that low overall plasma concentrations of gut microbiotaproduced BB in humans may be the result of microbial BB breakdown into TMA, predominantly occurring in the lower intestinal track (colon) distal to the absorption of most nutrients like l-carnitine and BB